The innate immune system serves as the body's first line of defense against pathogens. It includes physical barriers, such as the skin and mucous membranes as well as cellular components like macrophages, neutrophils, and dendritic cells. These elements work together to recognize common features of microbes through pattern recognition receptors and initiate an immediate immune response. Which of the following statements about the innate immune system is true?

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Deficiencies in innate immunity significantly increase host susceptibility to infections, even when the adaptive immune response is intact

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The innate immune response can be divided into specific recognition, activation, memory, and regulation

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Innate immunity is more effective at eliminating pathogens than adaptive immunity

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The innate immune system produces highly specific antibodies tailored to recognize unique antigens from a previous pathogen and provides long-term immune memory

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The innate immune response targets self-tissues

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