A developing thymocyte in the cortex interacts with thymic
epithelial cells. It expresses a TCR on its surface and both CD4 and CD8 coreceptors.
The TCR engages with an MHC class I molecule with a self-peptide that is
sitting in the binding cleft of the MHC. In this situation the cell will become
a CD8 positive T cell because:

Question

Accepted Answer

The CD8 molecule binds to the MHC I molecule.

Answer

The CD4 molecule does not bind to the MHC class
I molecule

Answer

The TCR binds to the MHC class I molecule

Answer

This is a false statement because TCR will not
bind to MHC presenting self-peptides

Crowdly

A developing thymocyte in the cortex interacts with thymic epithelial cells. It...

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