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What is calcium's key role in the release of transmitter from vesicles into the synaptic cleft?
Intracellular calcium must decrease 500-1000 fold for neurotransmitter release
Calcium is continuously present in the terminal, facilitating the constant release of neurotransmitter
Calcium controls the docking process of vesicles at the active zone, for fusion to the membrane
Voltage-gated calcium channels regulate the release of calcium into the terminal
Calcium is present at high concentrations within the active zone of the terminal membrane
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