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What is the effect on a developing embryo of treatmentwith a high dose of retinoids during early embryogenesis?
What is the effect on a developing embryo of treatment
with a high dose of retinoids during early embryogenesis?
Similar effects to those produced by
insufficient retinoic acid signalling.
Impaired
somitogenesis but unaffected craniofacial and limb development.
Increased
production of retinoic acid synthesising enzymes.
Sustained
increase in retinoic acid signalling during development.
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