You are studying the mechanisms underlying human heart development, in the hope of uncovering  novel therapies aimed at re-building heart tissue in those that have suffered damage (e.g. cases of heart attack).  For this reason, you are working with a variety of different bio-engineered hearts. 

You are organising the heart mutant protypes in your research notebook:  Match the mutant with the phenotypes that directly arise from the mutation in combination with the normal phenotypes present because of the mutation.  More than one answer may apply.

CV.mut.3: probe-patent foramen ovale