Each mature B cell expresses a single, unique antigen
receptor generated during development, allowing the immune system to recognise
a wide range of potential antigens. In a normal immune response, antigen
exposure leads to selective activation and rapid expansion of only those B
cells whose receptors bind the antigen, while unrelated B cells remain
inactive.

In a hypothetical organism that lacks clonal
selection but retains all other features of adaptive immunity, which finding,
after immunisation with a single purified protein would most clearly
differentiate it from a normal system?

Question

Each mature B cell expresses a single, unique antigen
receptor generated during development, allowing the immune system to recognise
a wide range of potential antigens. In a normal immune response, antigen
exposure leads to selective activation and rapid expansion of only those B
cells whose receptors bind the antigen, while unrelated B cells remain
inactive.

In a hypothetical organism that lacks clonal
selection but retains all other features of adaptive immunity, which finding,
after immunisation with a single purified protein would most clearly
differentiate it from a normal system?

Answer

Generation
of antibodies against multiple epitopes on the same antigen

Answer

Progressive
increase in antibody affinity after repeated exposure

Answer

Long-term
maintenance of antigen-specific plasma cells

Answer

Simultaneous
proliferation of many B cells regardless of receptor specificity

Crowdly

Each mature B cell expresses a single, unique antigen receptor generated during...

Want instant access to all verified answers on learning.monash.edu?