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Q2f.  The patient previously discontinued a Combined Oral Contraceptive (COC) du...

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Q2f. 

The patient previously

discontinued a Combined Oral Contraceptive (COC) due to nausea and breakthrough

bleeding. The estrogenic component of most COCs is Ethinyl Estradiol (EE) or

Mestranol (shown below). Why are these synthetic estrogens used in oral

contraceptives instead of natural 17β-estradiol, and how do they differ

chemically from one another?  (2 marks)

     

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