The nature and structure of the mucosal immune system are distinctive. CD8+ intraepithelial lymphocytes (IELs) interact with?

Question

Answer

MHC class II

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A specific receptor; therefore, IELs are subdivided into unlicensed and licensed IELs

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Other CD8 molecules, but do not have CD8 molecules on their cell surface

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The self-specific receptor of IEL, such as KIR, must interact with self-MHC I molecules from the target cell to be functional

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MHC class I polypeptide-related sequence A (MIC-A)

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