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Glycogen metabolism must be tightly controlled in the cells. If both processes h...

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Glycogen metabolism must be tightly controlled in the cells. If both processes happen at the same time, energy would be wasted. Glycogen metabolism is regulated in two ways:

  • Allosteric control of regulatory enzymes.

  • Hormonal control by covalent modification of regulatory enzymes.  

Typically, products of a pathway allosterically interact with a regulatory enzyme and inhibit them while a building block of a pathway allosterically interacts with a regulatory enzyme and activate them.

 

What would happen to glycogen phosphorylase and glycogen synthase if there is a high amount of ATP in the cell?

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