They suggested that meiotic-spindle transfer is ineffective in eliminating mutant mtDNA from embryos and requires further investigation

They found that the timing of nuclear transfer, before or after fertilization, significantly impacts the success of meiotic-spindle transfer

They successfully produced blastocyst-stage embryos with negligible amounts of mutant mtDNA using meiotic-spindle transfer

They concluded that pronuclear transfer is more effective than meiotic-spindle transfer in eliminating mutant mtDNA from embryos