There is a growing concern about the number of treatments that are successful in animal models but fail in clinical trials.
Which of the following is MOST likely contributing to the lack of translation?

Question

There is a growing concern about the number of treatments that are successful in animal models but fail in clinical trials.

Which of the following is MOST likely contributing to the lack of translation?

Answer

Preclinical research can often have inadequate sample sizes/animal numbers and there is a lack of collaboration between researchers and clinicians

Answer

Many animal models do not replicate the human disease and there are too many varying models of the disease that are examined

Answer

Preclinical
research lacks advanced technology and equipment and there is a lack of
commercial investment

Answer

There
is a lack of understanding of the human biology and there is a lack of
scientific data being published

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