B cells each express a unique antigen receptor before
encountering antigen. During an immune response, only B cells whose receptors
can bind a given antigen are activated and undergo rapid proliferation.

A hypothetical immune system lacks clonal
selection but retains all other features of adaptive immunity. Following
exposure to a single protein antigen, which outcome would most strongly
distinguish this system from a normal B-cell response?

Question

B cells each express a unique antigen receptor before
encountering antigen. During an immune response, only B cells whose receptors
can bind a given antigen are activated and undergo rapid proliferation.

A hypothetical immune system lacks clonal
selection but retains all other features of adaptive immunity. Following
exposure to a single protein antigen, which outcome would most strongly
distinguish this system from a normal B-cell response?

Answer

Production
of antibodies recognising multiple regions of the same antigen

Answer

Significant
activation of B cells with related antigen specificities to recognise a
specific antigen

Answer

Widespread
activation of B cells with diverse, unrelated antigen specificities

Answer

Gradual
improvement in antibody binding strength over time

Crowdly

B cells each express a unique antigen receptor before encountering antigen. Dur...

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