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During the stay in the maternity hospital, the newborn has a problem. The meconi...

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During the stay in the maternity hospital, the

newborn has a problem. The meconium does not pass (meconium is the first

content of the intestine to be passed during the first 1-2 days). After

examination, the so-called Hirschsprung disease

(megacolon congenitum)

is

proven. This disease is caused by abnormal innervation of the intestine,

affecting the internal anal sphincter and various lengths of adjacent colon.

Both the

plexus myentericus Auerbachi and the

plexus submucosus

Meissneri

are absent in the affected section of bowel. The aganglionic

section is permanently contracted (lacking inhibitory neurons) and causes

functional obstruction. The healthy intestine above it dilates and

hypertrophies to form megacolons. Where would we locate the plexus myentericus

within the wall?

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