The phenomenon of primary hyperalgesia that occurs to damaged skin is due to

Question

Accepted Answer

Sensitization of nerve ending TRPV1 channels by local chemical mediators from damaged tissue

Answer

Sensitization of nerve ending mechanically-gated ion channels by white blood cells from damaged blood vessels

Answer

Sensitization of nerve voltage-gated ion channels by local chemical mediators from damaged tissue

Answer

Sensitization of nerve voltage-gated ion channels by white blood cells leaking from damaged blood vessels

Answer

Sensitization of nerve ending voltage-gated ion channels by white blood cells from damaged blood vessels

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