Question 6: Experimental scenario [10 marks]. a) Imagine you are a research...
✅ The verified answer to this question is available below. Our community-reviewed solutions help you understand the material better.
Question 6: Experimental scenario [10 marks].
a)
Imagine
you are a research scientist studying defects of the vertebral column in
mammals. You wish to conduct a forward genetic screen for novel genes playing a
role in mouse vertebral column development. Using FOUR dot points and
no
diagram
, name this method and outline the steps involved in conducting such a screen for novel genes
that have an effect on vertebral development when recessive. (Hint, see Dr Alex Combes lecture # 10). (4 marks).
b) Imagine you have identified a novel gene using the approach in (a) above. How might you test if this gene has a conserved role in zebrafish vertebral column development? Without using a diagram, outline a method and the expected outcome. (4 marks).
c) How might you determine if the gene identified plays a role in human scoliosis (which is a vertebral defect)? What control would you use? (2 marks).Want instant access to all verified answers on learning.monash.edu?
Get Unlimited Answers To Exam Questions - Install Crowdly Extension Now!