A patient with RA and moderate disease activity is started on a TNF-inhibitor. What is a potential infusion-related reaction management strategy?

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Answer

Administer a live influenza vaccine immediately before the infusion.

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Pre-treat with intravenous immunoglobulin.

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Administer the infusion at the maximum flow rate to minimize the patient's time in the clinic.

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Hold all other DMARDs on the day of infusion.

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Pre-treat with acetaminophen, diphenhydramine, and a corticosteroid.

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