Based on the article and the lecture, which combination of laboratory findings is MOST consistent with Gilbert's syndrome and sufficient to make the diagnosis without invasive investigation?

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Total bilirubin markedly elevated with completely absent UGT1A1 activity and a high risk of kernicterus

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AST:ALT ratio greater than 2:1 with AST rarely exceeding 300 IU/L and a history of significant alcohol use

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Isolated unconjugated hyperbilirubinemia with a direct fraction below 15% of total bilirubin, normal aminotransferases and ALP, and absence of hemolysis

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Predominantly conjugated hyperbilirubinemia with a direct fraction greater than or equal to 15% of total bilirubin and normal aminotransferases

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Serum bilirubin reduction of more than 25% after a phenobarbital trial, fulfilling the diagnostic criterion for this specific syndrome

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Based on the article and the lecture, which combination of laboratory findings i...

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