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Activated DCs and T cells express CCR7 so that:

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Activated DCs and T cells express CCR7 so that:

They both migrate to the same regions within a lymph node

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There is strong adhesion during the interaction of TCR with the peptide:MHC

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They confirm their antigen specificity before the T cell differentiates into a T helper cell

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They are able to enter the B cell follicle to facilitate the germinal centre reaction

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