What is a proven benefit of combined ARNI (sacubitril/valsartan) therapy compared to angiotensin receptor blocker (ARB) alone in patients with heart failure with reduced ejection fraction (HFrEF)?

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Answer

Worsened quality of life

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No difference in outcomes

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Increased risk of hospitalization

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Improved survival and reduced risk of cardiovascular death

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What is a proven benefit of combined ARNI (sacubitril/valsartan) therapy compare...

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