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When a bacteria is coated with C3b or antibody, it can promote phagocytosis. This is because:
Antibody can bind to C3b and cross-link bacteria and phagocyte, allowing efficient phagocytosis
The phagocyte has surface molecules that can bind to C3b and antibody
C3b and antibody can bind to surface PRRs on the phagocyte and trigger phagocytosis
C3b and antibodies can lyse the bacteria, releasing PAMPs for recognition by phagocytes (primarily macrophages)
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