Smooth muscle can only be stimulated to contract by the CNS.

In smooth muscle, actin filaments and associated myosin attach to regular Z lines producing a striation pattern.

Calcium-dependent phosphorylation of myosin light chains is responsible for the contraction of smooth muscle.

Smooth muscle cells are multi-nucleated like cardiac and skeletal muscle cells.

Myocytes in single-unit smooth muscle are not electrically coupled to each other.