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An ICU surveillance program detects a multidrug‑resistant Acinetobacter bauman...
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An ICU surveillance program detects a multidrug‑resistant solate causing septicaemia. Susceptibility testing demonstrates poor activity of carbapenem antibiotics, while polymyxins remain effective. Molecular analysis identifies a plasmid‑borne gene encoding a β‑lactam–hydrolyzing enzyme.
Which antimicrobial resistance mechanism best accounts for this resistance pattern?
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