QInB=33

Fentanyl (Actiq) is primarily eliminated by CYP3A4 metabolism, and renal clearance of the drug is negligible. What is the most accurate statement regarding this information?

Question

QInB=33
 
   Fentanyl (Actiq) is primarily eliminated by CYP3A4 metabolism, and renal clearance of the drug is negligible. What is the most accurate statement regarding this information?

Answer

The drug is expected to undergo pharmacokinetic interactions with many drugs commonly used in clinical practice.

Answer

This is a standard and typical case. There’s no need for concern. The drug is expected to undergo pharmacokinetic and pharmacodynamic interactions with only a few drugs.

Answer

No dose adjustment is required for patients with impaired kidney function.

Answer

The drug has a high potential for renal toxicity due to its low renal clearance.

Answer

No dose adjustment is required for patients with impaired liver function.

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QInB=33 Fentanyl (Actiq) is primarily eliminated by CYP3A4 metabolism, and ...

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