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•Biophase model – Berkeley Madonna code Biophase.txt •Single bolus dose, one c...

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•Biophase model – Berkeley Madonna code Biophase.txt

•Single bolus dose, one compartment PK

•Biophase model describing delay due to distribution of drug to site of action (biophase, hypothetical effect compartment), with baseline, i.e. the effect is at 1 without any drug

Simulate (in overlay mode) Effect over time for escalating doses, e.g. between 10 mg and 2,000 mg and observe what happens with the shapes of the profiles as the dose increases

Upload an image of the PK/PD profiles (Effect over time, i.e. the PK/PD profiles) onto Moodle
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