Learning activities

iv. Clinical trials involving medicines

Match the following:

Match the following descriptions to match their corresponding clinical drug trial phase:

• Statement A - To assess pharmacokinetics and preliminary data on drug bioavailability
• Statement B - To assess drug safety; to assess tolerance; drug pharmacokinetics / pharmacodynamics and identify preferred routes of administration
• Statement C - To assess drug efficacy and further assess safety through pilot studies; to explore the therapeutic dose range
• Statement D - To assess drug efficacy and determine optimum therapeutic dose and regimen to inform conduct of subsequent trials
• Statement E - To test medicine efficacy in large groups of participants for whom the drug is eventually intended; to test efficacy by comparing new drug to other standard or experimental drugs; to monitor for rare side effects
• Statement F - Post marketing surveillance or resolution of treatment uncertainties; Monitor safety in real world populations; Trial combinations with existing products