Activated B cells can alter the class of antibody they
produce, changing how antibodies interact with Fc receptors and complement
while preserving antigen specificity. This process allows the immune system to
tailor effector responses to different stages or types of infection.

Which experimental result would most strongly
support that class switch recombination has taken place?

Question

Activated B cells can alter the class of antibody they
produce, changing how antibodies interact with Fc receptors and complement
while preserving antigen specificity. This process allows the immune system to
tailor effector responses to different stages or types of infection.

Which experimental result would most strongly
support that class switch recombination has taken place?

Answer

Antibodies
shift from cell-bound to secreted forms, but have CDR regions which are the
same

Answer

Point
mutations accumulate within complementarity determining regions

Answer

Antibodies
with identical variable regions are detected as IgG, IgA, and IgE

Answer

Antibody
affinity for antigen increases over time

Crowdly

Activated B cells can alter the class of antibody they produce, changing how an...

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