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Oscar was diagnosed with infection by the Sesame Street Virus (SSV).  SSV is a ...

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Oscar was diagnosed with infection by the Sesame Street Virus

(SSV).  SSV is a single-stranded,

negative-sense RNA virus (pictured below). 

Image failed to load: SSV

(A)   The SSV

virion pictured above has glycoprotein spikes on the surface of the virion

(structure A).  What is the function of

this glycoprotein in the viral life cycle?

(B)   Viruses

survive by hijacking host cell machinery to express viral proteins.  The schematic of the SSV virion shows a

protein, labelled Viral protein X.  

Viral protein X is necessary for both viral genome replication and

protein expression.  What type of protein

is viral protein X and why is it packaged into the virion? 

(C)   Explain

how SSV will express proteins such as Structure C shown in the diagram of the

virion.

(D)   SSV has

replicated in Oscar’s cells. In the diagram of the SSV virion, what is

structure B and how is it formed?

[1 + 2 + 3 + 2 = 8 marks]

[max. 300 words]

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