GABA is a transmitter in the CNS which binds to ionotropic receptors to allow the influx of Cl^-. The figure below shows the size of the water-filled pore of the channel under three conditions. the second condition shows the pore size with binding of GABA and a benzodiazepine agent to the receptor, and the third condition shows the pore size with binding of GABA, the benzodiazepine and a Barbiturate agent to the receptor.. Comparing the three cases,you would expect
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Question

GABA is a transmitter in the CNS which binds to ionotropic receptors to allow the influx of Cl^-. The figure below shows the size of the water-filled pore of the channel under three conditions. the second condition shows the pore size with binding of GABA and a benzodiazepine agent to the receptor, and the third condition shows the pore size with binding of GABA, the benzodiazepine and a Barbiturate agent to the receptor.. Comparing the three cases,you would expect

Image failed to load: GABA pore size

Answer

That the antagonism of GABA effects by benzodiazepine would not be made any bigger by barbiturate

Answer

That the effects of GABA would be totally antagonized by benzodiazepine and barbiturate

Answer

That the effects of GABA would be partially antagonized by benzodiazepine

Answer

That the greatest amount of post-synaptic membrane potential de-polarization would occur with the binding of all three agents

Answer

That the greatest amount of post-synaptic membrane potential hyper-polarization would occur with the binding of all three agents

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GABA is a transmitter in the CNS which binds to ionotropic receptors to allow th...

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