The bacterium Salmonella enterica Typhoid initially invades intestinal epithelial cells within which the bacterium replicates. While located intracellularly the Salmonella bacterium produces a potent gastrointestinal toxin (called Typhoid toxin) that interferes with the aquaporins in the intestinal wall that normally maintain osmotic balance. The result is the influx of water into the gastrointestinal lumen causing profuse diarrhea.
What would you consider the ultimate cause of the release of the Typhoid toxin?

Question

The bacterium  Salmonella enterica  Typhoid initially invades intestinal epithelial cells within which the bacterium replicates. While located intracellularly the Salmonella bacterium produces a potent gastrointestinal toxin (called Typhoid toxin) that interferes with the aquaporins in the intestinal wall that normally maintain osmotic balance. The result is the influx of water into the gastrointestinal lumen causing profuse diarrhea. 
 What would you consider the  ultimate cause  of the release of the Typhoid toxin?

Answer

Increases the concentration of key nutrients in the lumen of the intestinal tract

Answer

The influx of water into the lumen creates a benefit to the host as it aides in fluid acquisition in the colon

Answer

Helps to ‘flush out’ resident adaptive immune cells (such as B cells) in the gut cavity, helping the bacterium evade the immune response

Answer

The profuse diarrhea promotes the transmission of the infection to a new host

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The bacterium Salmonella enterica Typhoid initially invades intestinal epithe...

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