A mutation causes constitutive overexpression of a multidrug
efflux pump, conferring reduced susceptibility to several antibiotic classes.
The mutation carries a modest metabolic cost but provides survival advantage
during antibiotic exposure.

If antibiotics are intermittently used in the
environment, what pattern of selection is most likely?

Question

A mutation causes constitutive overexpression of a multidrug
efflux pump, conferring reduced susceptibility to several antibiotic classes.
The mutation carries a modest metabolic cost but provides survival advantage
during antibiotic exposure.

If antibiotics are intermittently used in the
environment, what pattern of selection is most likely?

Accepted Answer

Directional
selection favouring efflux‑overexpressing variants

Answer

Diversifying
selection based on drug class

Answer

Stabilizing
selection maintaining efflux at basal levels

Answer

Negative
selection eliminating the mutation

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A mutation causes constitutive overexpression of a multidrug efflux pump, confe...

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