Within the cell, different triggers of the inflammasome will lead to the production of different inflammatory cytokines.

Pro-IL-1b is active but must be cleaved to be secreted from the cell.

The inflammasome is only activated upon contact or detection of microbial products.

In order to be functional, caspace-1 must first be cleaved to a smaller molecule.

advanced systems of water management

a series of sea walls called dikes

The old system of building dikes did not offer enough protection.

It was good farming land, but it was rarely visited.

It needed a better water management system.