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Which statement/s is/are correct about collagen?

Collagen fibres are basophilic.

Tropocollagen molecules aggregate into microfibrils which form fibrils.

Tropocollagen is formed by a double helix of two polypeptide chains.

It contains abundant amino acids glycine and proline (or hydroxyproline).

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Reticular tissue

forms the stroma of the hematopoietic bone marrow.

forms the fibrous capsule (capsula fibrosa) of the spleen, kidney, and liver.

its reticular cells produce and envelop the reticular fibers with their processes.

usually contains no phagocytic cells.

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Reticular fibres

do not stain when impregnated with silver.

consist mainly of type IV collagen.

are in the connective tissue of the bone marrow.

are surrounded by smooth muscle cells in the arterial wall.

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Melanocytes (pigment cells)

form melanosomes with a group of tyrosine-derived pigments.

have long processes.

are ontogenetically derived from the intestinal endoderm.

release melanin granules in the epidermis into the surrounding keratinocytes.

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Mast cells (mastocytes)

contain granules of heparin and histamine.

have membrane receptors for IgE.

are found e.g. in the connective tissue of the dermis and in the lamina propria mucosae of the digestive and respiratory tract.

are hepatic cells in the wall of canals of Hering.

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has abundant rough endoplasmic reticulum and Golgi complex.

can differentiate into a fibrocyte.

is a very common connective tissue cell.

is no longer able to synthesize extracellular matrix.

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Which statement/s is/are correct about histological staining of connective tissue?

In hematoxylin-eosin staining, collagen is basophilic.

Orcein stains elastin brown.

PAS (Periodic Acid Schiff) method stains polysaccharides and glycosaminoglycans.

In green trichrome staining, collagen stains green.

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gives rise to different types of epithelia during ontogenesis.

is an undifferentiated embryonic connective tissue.

remains avascular, i.e. does not contain blood vessels.

contains proliferating cells.

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Which statement/s is/are correct about structural glycoproteins?

An example is chondroitin sulfate in cartilage.

Laminin mediates the adhesion of epithelial cells to the basal lamina.

Fibronectin mediates the association of cells with collagen and glycosaminoglycans.

Chondronectin binds chondrocytes to type II collagen.

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Brown adipose tissue

is in the newborn, e.g. around the kidneys, in the neck and between the scapulae.

is innervated by sympathetic autonomic fibres.

is important for non-shivering thermogenesis, i.e. the production of body heat independent of skeletal muscle activity.

is mainly composed of unilocular adipocytes and is almost avascular, i.e. it does not contain blood vessels.

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