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MECHANISM OF DISEASES I A001843 2025-2026
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Order the following stages of scar formation: 1.Proliferation of fibroblasts; 2.Degradation of collagen / ECM by metalloproteinases; 3. Deposition of extracellular matrix, collagen synthesis; 4. Migration of fibroblasts to site of injury; 5.Vascular regression; 6. Granulation tissue formation
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Which of the following is TRUE referring to wound healing
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A 5-year-old child is brought to the emergency department by his parents for right arm pain. The patient reports that he was playing hide and seek outside and felt a sharp pain on his arm while hiding in some thick bushes. His parents suspect that something had stung him. Physical examination shows an edematous and erythematous plaque with mild central pallor. A residual stinger, located central to the lesion, is readily extracted. The physical examination is otherwise not significant. Which of the following substances is most likely directly responsible for the skin findings observed in this patient?
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Which of the following is TRUE referring to acute inflammation
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9. The most characteristic feature of granulation tissue is the
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With regard to natural killer lymphocytes
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Which is not chemotactic?
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3. A scientist is interested in the mechanism of leukocyte traffic to site of inflammation. She finds that endothelial cells increase the expression of certain adhesion molecules in response to cytokines. She creates a knockout mouse that has a deletion in the E-selectin gene. Absent expression of this gene will most likely affect which of the following neutrophil functions?
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Leukocyte extravasation occurs in the following order:
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Which of the following is the more correct definition of a lung granuloma?
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