Intracellular molecules accumulate near the antigen receptors

The cells release toxic substances to kill the antigen

The antigen receptor with antigen is released from the cell to stimulate inflammation

The cell divides to make more clones of itself 

PD-1

CD28

ITAM

CD4

Predominantly in the CDR1 region of the heavy and light chains

Predominantly in the variable region of the heavy chain

Evenly distributed over the entire length of the heavy and light chains

At the antigen binding sites of the heavy and light chains

The B cell receptor conforms to the shape of the pathogen once encountered

Most B cells secrete low levels of antibody to maintain homeostatic antibody levels

Each B cell generates its B cell receptor in the same way as T cells

The B cell receptors are only generated after engagement of TLRs by PAMPs

Cytokines

Chemokines

Co-stimulatory molecules

Interaction of TCR with peptide:MHC

Directing the differentiation of naïve T cells

Opsonising the microbe to be cleared by phagocytes

Directing the microbe to lymph nodes to initate an immune response

Binding to cytokine receptors on the microbe to induce lysis

The phosphorylation of CD4 on the surface of the T cell

The binding of the TCR to peptide:MHC class II on the macrophage

The binding of CD40 on the T cell to CD40L on the macrophage

The release of IFN-γ by the activated TH1 cell

Loss of MHC expression in infected macrophages

Increased M1 macrophage activity

Increased M2 macrophage activity

Inhibition of all macrophage effector mechanisms in infected, and local, macrophages

To promote macrophage proliferation

To inhibit inflammation

To adsorb any local TH1 cytokines, to further polarise the response towards a TH2 response

The same as TH1 cells, to activate macrophages to eliminate intracellular pathogens (using different cytokines)