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PHY2011 - Neuroscience of communication, sensory and control systems - S1 2025

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The nerve supplying a cat soleus muscle consists of 541 myelinated axons, of which 62% are motor. Of these motor axons, 22% supply muscle spindles and, therefore, do not contribute to the force developed by the contracting muscle.

Of how many motor units is this soleus muscle composed ?

Answer in whole numbers, with no decimal places.

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A cat soleus muscle is composed of 32861 muscle fibres. Assume that the force developed by a motor unit is proportional to the number of muscle fibres it contains. If the maximum tetanic force developed by the soleus muscle is 20.4 Newtons (N), calculate the number of muscle fibres in the smallest motor unit, if this motor unit develops a force of 33 milliNewtons (mN).

Answer in whole numbers, with no decimal places.

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A myelinated nerve fibre has a conduction velocity of 118 m/sec and internode lengths of 1.1 mm.

How long does it take an action potential to spread from one node of Ranvier to the next ?

Answer in milliseconds to 3 decimal places.

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A large motor neuron with a diameter of 18 m

m has a conduction velocity of 137 m/sec. If its length from the spinal cord to the muscle it innervates is 1m, how long would it take an AP at the cell body (in the spinal cord) to reach the muscle ?

Answer in seconds to 3 decimal places.

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A Beaker is divided into two chambers, A and B, by a semi-permeable membrane lying across the middle of the beaker.

Chamber A contains the following concentration of ions:

{Na+} = 58 mM,, {K+} = 141 mM, {Cl-} = 100 mM, {A-} = 106 mM

Chamber B contains the following concentration of ions:

{Na+} = 200 mM,, {K+} = 9 mM, {Cl-} = 50 mM, {A-} = 152 mM

If the membrane is permeable only to K

+

, what is the transmembrane potential difference of Chamber A relative to Chamber B?

Answer in whole numbers, with no decimal places. In your answer give only the numerical (asbolute) value - i.e., ignore the sign of the answer.

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A Beaker is divided into two chambers, A and B, by a semi-permeable membrane lying across the middle of the beaker. Chamber A contains the following concentration of ions:

{Na+} = 21 mM, {K+} = 100 mM, {Cl-} = 110 mM

Chamber B contains the following concentration of ions:

{Na+} = 107 mM, {K+} = 10 mM, {Cl-} = 110 mM

If the membrane is permeable only to Na+, what is the transmembrane potential difference of Chamber A with respect to Chamber B?

Answer in whole numbers, with no decimal places. In your answer give only the numerical (asbolute) value - i.e., ignore the sign of the answer.

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For the statement in the left column select the correct term from the drop down list. Terms may be used more than once.

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