You have been given this lipid.

If you mix it with the compound below, which functional groups will the lipid react to? Choose every functional group that can react with the lipid. Marks are given for every correct functional group selected; marks are lost for identifying incorrect functional groups.

Based on the DLS corellograms below, which of the following statements are true.

Which of the following statements about liposomes are true?

From the following list, select the reactive group that would be required on the surface of the liposome that would enable attachment of the molecule via the functional group you selected.

What is the name of the functional group you have selected?

You have been given the following lipid to formulate into a lipid nanoparticle to deliver mRNA. When assembling the nanoparticle, in addition to this lipid, what else do you need?

You wish to develop a formulation of a hydrophilic drug to treat lymphoma. You have 5 possible types of formulation you could use:

1) Cyclodextrin

2) Micelle

3) Liposome

4) Lipid Nanoparticle

5) SEDDS

Which of these formulations would be best to deliver the drug? Choose only one (1) formulation. Explain why the other formulations would not be appropriate (give one reason for each formulation).

You wish to develop a formulation of mRNA to treat cystic fibrosis. You have 5 possible types of formulation you could use:

1) Cyclodextrin

2) Micelle

3) Liposome

4) Lipid Nanoparticle

5) SEDDS

Which of these formulations would be best to deliver mRNA? Choose only one (1) formulation. Explain why the other formulations would not be appropriate (give one reason for each formulation).

From this graph determine the intrinsic solubility of the drug.

Based on the structure of this surfactant (which has has a hydrophobic to hydrophilic ratio of 1:1), which of the following statements are true?