14 kJ/mol

10 kJ/mol

20 kJ/mol

18 kJ/mol

Low anaerobic power, greater abundance of fast twitch muscle fibres and hypertrophy of the quadriceps (leg) muscles.

High anaerobic power, greater abundance of fast twitch muscle fibres and hypertrophy of the quadriceps (leg) muscles.

High anaerobic power, greater abundance of fast twitch muscle fibres and hypertrophy of the biceps (arm) muscles.

High anaerobic power, lower abundance of fast twitch muscle fibres and hypertrophy of the quadriceps (leg) muscles.

Increased anaerobic metabolism

Decreased mitochondrial proteins

Decreased metabolite influx

Increased oxidative metabolism

It increases

It decreases

It remains the same

It initially decreases, but later increases

 Blood flow remains unchanged during contraction, while compressive regions increase their vascularity to offset metabolic demands.

Blood flow increases are proportional across all tendon regions, eliminating site-specific injury risk.

The rise in blood flow primarily supports surrounding muscle, with negligible benefit for tendon cellular metabolism.

 Increased blood flow during loading supplies ATP for collagen synthesis, promoting efficient repair; however, compressive regions with fibrocartilage show less vascular response, predisposing them to degenerative changes.

Two-way ANOVA

One-way ANOVA

T-test

Correlation analysis

30 s

10 s

50 s

60 s

The presence of inhibitors saturates the enzyme

More enzyme is present than substrate

The activation energy of the reactants is too high

More substrate is present than enzyme

ADP turns into ATP to provide energy to convert myosin heads into ‘cocked’ state

Calcium binds to actin to allow troponin binding to myosin

ATP binds to myosin making it detach from actin

Actin pushes on myosin to complete a power stroke

Low mitochondrial density & high capillary density

High mitochondrial density & low capillary density

Low mitochondrial density & low capillary density

High mitochondrial density & high capillary density