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علم الأدوية 1 - الامتحان الموحد
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Which of the following drugs is commonly used topically in the treatment of glaucoma?
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A 45-year-old male complains of constipation. He was recently started on two antihypertensives due to elevated systolic blood pressure {greater than 20 mm Hg above goal). His current medications include lisinopril, chlorthalidone, verapamil, rosuvastatin, and aspirin. Which is most likely contributing to his constipation?
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Haloperidol, chlorpromazine, and clozapine are antipsychotic medications that bind to the D2 subtype of dopamine receptors, with a binding affinity of haloperidol > chlorpromazine > clozapine. Which statement would have to be correct to conclude that the mechanism of antipsychotic effects for these drugs is via binding to D2 receptors?
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Which can precipitate a hypertensive crisis following abrupt cessation of therapy?
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A new antihypertensive drug was tested in an animal model of hypertension. The drug when given alone reduces blood pressure in the animal. Norepinephrine when given in the presence of this drug did not cause any significant change in blood pressure or heart rate in the animal. The mechanism of action of the new drug is similar to which of the following agents?
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A 52-year-old female has uncontrolled hypertension (blood pressure 154/82 mm Hg) on treatment with lisinopril. She recently had a myocardial infarction and her past medical history includes diabetes, hypertension, hyperlipidemia, and osteoarthritis. Considering her compelling indications, which agent may be appropriate to add to her antihypertensive therapy?
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