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YEAR-1 Course management

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An 8-year-old girl has early puberty and short stature. She is treated with an allosteric modifier. Which is the most likely mechanism of allosteric regulation in this case?

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A 48-year-old man is admitted to the hospital with severe abdominal pain. Radiographic examination reveals a tumor in the tail of the pancreas. A diagnostic arteriogram shows that the tumor has compromised the blood supply to another organ. Which organ is most likely to have its blood supply compromised by this tumor?

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A 2 days-old male infant is born with herniation of intestine into umbilicus. Prenatal ultrasound scans during the pregnancy showed an abnormality of the anterior abdominal wall, which was suspected to be an omphalocele. At which week of development does failure of return of the intestinal lobe typically occur in this baby?

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A researcher wants to measure the extracellular fluid (ECF) volume for a group of adult men.

What is the most likely substance would he use?

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Mr. Ahmed has a peptic ulcer. His physician prescribes a drug that inhibits gastric acid secretion by blocking H2-recpetors. Which of the following drug is most likely prescribed?

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A 35-year-old woman presents with flatulence, bloating, and steatorrhea. Normally, dietary triacylglycerol is hydrolyzed in the intestine into components that can be easily absorbed. Which enzyme is most likely deficient in this case?

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A 70 year old man with uncontrolled diabetes mellitus for 30 years is referred to the nephrologist as he started to he has cloudy frothy. The physician suspects proteinuria.

Which is the most likely mechanism of the patient’s condition?

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A 55 year old woman with chronic kidney disease (CKD) visits the primary health care with progressive fatigue and pallor, investigations show normocytic normochromic anemia.

Which is the most likely kidney-related mechanism that best explains her condition?

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TCA cycle is also known as the amphibolic pathway (functions both in oxidative and synthetic processes). Which is the most likely enzyme that catalyzes co-reduction of FAD to FADH2 in this cycle?

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Water soluble vitamins have an important metabolic role in the human body.

What best describes water-soluble vitamins?

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