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Phase 3 Medicine 2026

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The mother of a 16-year-old girl is brought to your Emergency Department. Her mother describes the onset of some changes in her behaviour over the last 2 days. The following is a list of her symptoms. You are concerned that her mother is describing delirium. Which of her symptoms below supports your provisional diagnosis?

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What is the primary difference between delirium and dementia?

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A 25-year-old woman, 50 kg, presents with nausea, vomiting and

abdominal pain for the last few hours. She has dental pain and has been taking 1g paracetamol orally every 4 hours for the last 3 days. 

On examination of her abdomen, you note it is soft, mildly tender in right upper quadrant. Paracetamol level is 35 mg/L, ALT 800 IU/L. HR 90 bpm, BP 100/70 mm Hg, temp 37.4°C.  

Nomogram

What is the most appropriate treatment for this patient?

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A 35-year-old male is brought in by ambulance with an overdose of

paracetamol. He was found by neighbours alone in his unit. He had written a

suicide note that says he took 50 tablets of 500mg, dated 3 days ago.

On arrival, he is jaundiced. HR 105, BP 105/90, RR 24, Temp

36.1. He is unable to follow commands and is disorientated to time place and

person.

His pathology findings are:

  • Bilirubin 82umol/L (1-20)
  • ALT 3890 U/L (5-40)
  • AST 7257 U/L (5-30)
  • Alkaline phosphatase 178 U/L (30-110)
  • Creatinine 0.30 mmol/L (0.60-0.11)
  • INR 6.9 (< 1.5)
  • Paracetamol level is 22 mg/L

Paracetamol treatment nomogram

Which

of the following is the most immediate management in the ED?

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For the same patient above, the paracetamol level at 4h is 200 mg/L. What is the next most appropriate step?

Paracetamol Treatment Nomogram (Rumack-Matthew Nomogram)

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A 54-year-old man is brought in by ambulance and police. He was

found not rousable on the street. The ambulance team thinks he might have

injected heroin. At the scene, his GCS was 15 then deteriorated to 10 enroute.

On examination in the ED, his RR is 10/min, SaO2 92% on room

air, HR 100/min, BP 90/70 mm Hg. He has pin-point pupils. You note a fresh IV

access mark (track mark) on the left side of his neck.

You have secured IV access and placed him on

cardiorespiratory monitoring with supplemental oxygen. His GCS is 8. HR 100

bpm, BP 85/50 mm Hg, RR drops to 4/min. SAO2 86% on oxygen.

Question:

Which of the following is the most appropriate

next action in the ED?

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A 23-year-old woman is brought to the ED by federal police from the

airport. They think she has ingested large amounts of drugs during her flight

from Bali. In fact, a female undercover policewoman witnessed her ingestion of

multiple bags of white substance in the toilet just before arrival at the

Sydney airport.

On examination, she looks well and has denied the ingestion

of any substance other than food. After her CT abdomen -pelvis, where several

discrete “packages” are evident, she admits to the ingestion of drugs. HR 100 bpm, BP 120/70 mm Hg, temp 36.5°C, RR

14/min, O2sat 98% on room air.

Question:

What is the most appropriate method of removing the drugs in

the ED?

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A 29-year-old man presents by ambulance after taking an

unknown amount of promethazine. The estimated time of ingestion is about 1 hour ago. His HR 90 bpm, BP 120/80 mm Hg. He is mildly confused but co-operative. What method of decontamination is most appropriate for him?

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A 38-year-old man is brought in by ambulance after an

intentional overdose of paracetamol of 500 mgx20 tablets. He is regretful of

his action and called the ambulance 7 hours after ingestion. HR 90 bpm, BP 120/80 mm Hg temperature 37.3°C. 

Question:

Which of the following is the most correct

regarding the antidote for paracetamol poisoning?

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An 80-year-old woman is brought in by her partner due to

recurrent episodes of syncope which are witnessed. There are no prodromal

symptoms. She is on metoprolol for hypertension and it was recently increased from 25 mg twice daily to 50 mg twice daily. 

On examination, she looks well. She does not describe any

prodromal symptoms prior to her syncopal episodes. On examination, HR 40 bpm, BP 130/80 mm Hg.

Question:

Which of the following conditions is most important to rule

out?

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