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A man died after a surgery for the perforation of the colon wall with signs of diffuse purulent peritonitis. Autopsy shows that the mucosa of the colon wall is thickened, covered in a fibrinous membrane, and has isolated ulcers that penetrate it to varying depths. Histology detects mucosal necrosis, the presence of fibrin, and leukocyte infiltration with hemorrhagic foci. What disease developed a complication in this case, causing the death of this man?
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A patient complains of acute pain attacks in the right lumbar region. During examination the nephrolithic obturation of the right ureter in the region between its abdominal and pelvic segments has been detected. What anatomical boundary exists between those two segments?
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За умов дії якого ферменту арахідонова кислота (джерело синтезу ейкозаноїдів) вивільняється з фосфоліпідного бішару клітинних мембран?
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After a cholecystectomy, the processes of Ca$^{++$ absorption through the intestinal wall became impaired in the patient. What vitamin must be prescribed to stimulate this process?
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A 14-year old girl presents to the emergency department for evaluation of an <<infected leg>>. She states there is no history of trauma but mentions she had a history of sickle cell disease. On physical examination, her upper part of right shin is very painful, red, swollen and hot. Her temperature is 39.2°C) An X-ray shows focal bony lysis and loss of trabecular architecture in the metaphysis of right tibia. Increased activity of which of the following cells is the most likely cause of bone reabsorption in this patient?
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A 35-year-old woman has come to her physician with chief complaint of elevated blood pressure up to 180/100 mm Hg. She currently does not take any medication. During the physical examination, her blood pressure is 140/80 mm Hg, heart rate is 65/min. and temperature is 36.8°C) She has a ''moon face'', hirsutism, centripetal obesity, and striae on the skin with atrophy over the abdomen and thighs. Which of the following is the most likely cause of this patient's condition?
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A 56-year-old man presents for a checkup. The patient says he has to urinate quite frequently, but denies any dysuria or pain on urination. Past medical history is significant for diabetes mellitus type 2 and hypertension, both managed medically. Current medications are metformin, aspirin, rosuvastatin, captopril and furosemide. Laboratory findings are significant for the following: Glycated Hemoglobin (Hb A1c) --- 8.0%, Fasting Blood Glucose --- 12 mmol/L. His doctor decides to add glibenclamide to the therapy. Which of the following is the most likely mechanism of this drug's action?
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A 65-year-old woman presents to the emergency department because of shortness of breath and chest pain that started a few hours ago. She did not have a fever, expectoration, or any accompanying symptoms. She has a history of right leg deep vein thrombosis that occurred 5 years ago. Some time later, she dies of severe respiratory distress. A pulmonary autopsy specimen reveals red loose mass that is lodged in the bifurcation of the pulmonary trunk with extensions into both the left and right main pulmonary arteries. Which of the following is the most likely diagnosis?
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A newborn delivered at 33 weeks of gestation has a respiratory rate of 70/min. and heart rate of 148/min. 2 hours after birth. He is grunting and has intercostal and subcostal retractions. He has peripheral cyanosis as well. An immediate chest radiograph is taken which shows a fine reticular granulation with ground glass opacity on both lungs. A neonatologist suggests respiratory distress syndrome due to surfactant deficiency. Which of the following is the most likely mechanism of these clinical and imaging findings?
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The molecule of immature mRNA (pro-mRNA) contains more triplets than there are amino acids in the synthesized protein, because translation is normally preceded by:
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