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Calcification of the intercellular substance of bone tissue is accompanied by the deposition of hydroxyapatite crystals along the collagen fibers. This process requires the presence of alkaline phosphatase in the intercellular matrix. Which of the following cells most likely produces this enzyme?
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A 40-year-old male comes to the physician because of recurrent painful flares and swelling of the metatarsal-phalangeal joint of the great toe. Laboratory study of urine sample shows extremely low pH and pink discoloration. Which of the following metabolic intermediates is the most likely cause of changes in this patient's urine?
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A 58-year-old man presents with the clinical picture of acute pancreatitis. This diagnosis can be confirmed by high levels of a certain substance in the patient's urine. Name this substance:
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During a selection for revaccination with the BCG vaccine, a schoolboy has undergone the Mantoux test that turned out to be negative. What does this test result indicate?
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The dentist should inject a local anesthetic to reduce pain sensation in the maxillary molars and adjacent facial soft tissue and gingiva. He inserts the needle through oral mucosa at the height of the maxillary vestibular fornix just posterior to the maxillary tuberosity. The needle is directed medially and superiorly toward the alveolar canals. Which of the following nerves is most likely to be blocked?
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A patient being treated for viral B hepatitis developed signs of hepatic failure. What changes in the blood test that indicate a protein metabolism disorder will most likely be observed in this case?
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A 43-year-old cattle farm worker is brought to the surgeon with fever, malaise, and inflamed lesions on his hands and arms. He reports that about 2 weeks before his presentation at the hospital he noticed small, painless, pruritic papules that quickly enlarged and developed a central vesicle. The vesicles developed into erosion and left painless necrotic ulcers with black, depressed eschar. Gram's staining of the ulcer reveals gram-positive spore-forming bacilli. Which of the following diseases is the most likely cause of these findings?
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A 35-year-old woman is brought to the physician because of a 4-month history of progressive weakness of both lower limbs. She notes difficulty climbing stairs and complains of lethargy and loss of muscle bulk. Her diet consists primarily of <<polished>> rice. A diagnosis of dry beriberi is suspected. Deficiency of which of the following vitamins is most likely to be detected in her blood?
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A patient with acute retention of urine has been brought to an admission room. During examination a doctor found out that the patient has urethral obturation caused by pathology of the surrounding organ. Name this organ:
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A patient feels pain and numbness in the gums of the upper jaw. What nerves are most likely to be damaged in this case?
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