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Basic Mechanism of Diseases

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Which of the

following cancers results in the highest absolute number of deaths of women in

the United States each year?

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 A 60-year-old man who has a history of cigarette smoking, (90 packs per year) had

a chronic cough for the past 10 years. He has begun to lose weight (3 kg)

during the past year. He has a chest radiograph that reveals a right hilar

mass. Sputum cytology shows atypical, hyperchromatic squamous cells. What is

the most common initial pathway for metastases from this lesion?

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A 16-year-old boy has noted pain in his left knee after each hockey practice

session for the past month. On examination, there is tenderness to palpation of

his left knee, with a reduced range of motion. X-Ray of the left leg reveals a

mass of the proximal tibial metaphysis that erodes bone cortex, where reactive

new bone is apparent. Microscopic examination shows atypical, malignant cells

with hyperchromatic nuclei in an osteoid stroma. Which of the following

neoplasms is he most likely to have?

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Which of the

following is not a cancer screening tool?

 

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Which of the following is

the most frequent site for Osteosarcoma?

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Identify the structure in the

photomicrograph marked by

C:

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A clinical

study is performed of patients with pharyngeal infections. The most typical

clinical course averages 3 days from the time of onset until the patient sees

the physician. Most of these patient’s experience fever and chills. On physical

examination, the most common findings include swelling, erythema, and

pharyngeal purulent exudate. Which of the following types of inflammation did

these patients most likely have?

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A

19-year-old woman who works indoors spends a day outside gardening. She does

not wear a hat or sunscreen. That evening her partner remarks that her face

appears red. Which of the following dermal changes most likely accounts for her

red appearance?

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A

43-year-old woman has had a chronic cough with fever and weight loss for the

past month. A chest radiograph reveals multiple nodules from 1 to 4 cm in size,

some of which demonstrate cavitation in the upper lobes. A sputum sample

reveals the presence of acid-fast bacilli. Which of the following cells is the

most important in the development of her lung lesions?

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A 70-year-old

man presents with the sudden onset of left-sided weakness, spasticity, and

hyperactive and pathologic reflexes. The most serious consequences of this

disorder are the result of damage to which of the following cell types?

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