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The anti-epileptic drug phenytoin, undergoes metabolism by the CYP450 enzyme, 2C...
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The anti-epileptic drug phenytoin, undergoes metabolism by the CYP450 enzyme, 2C9.
A patient who has been stable on phenytoin for several months, is prescribed a short course of fluconazole to treat a fungal infection. Fluconazole is a 2C9 inhibitor.
If taking phenytoin and fluconazole at the same time, which one of the following is this patient MOST LIKELY to be at risk of?
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