The beta-adrenoceptor antagonist, metoprolol is metabolised almost exclusively by CYP2D6.
Which of the following would MOST LIKELY occur if metoprolol is taken at the same time as diphenhydramine (Benadryl), a known CYP2D6 inhibitor?

Question

The beta-adrenoceptor antagonist, metoprolol is metabolised almost exclusively by CYP2D6.   
 Which of the following would MOST LIKELY occur if metoprolol is taken at the same time as diphenhydramine (Benadryl), a known CYP2D6 inhibitor?

Accepted Answer

decreased metabolism of metoprolol and increased risk of adverse effects

Answer

increased metabolism of metoprolol and an increased risk of adverse effects

Answer

increased metabolism of metoprolol and reduced therapeutic effectiveness

Answer

decreased metabolism of metoprolol and reduced therapeutic effectiveness

Crowdly

The beta-adrenoceptor antagonist, metoprolol is metabolised almost exclusively b...

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