In the clinical context of the article, the patient has confirmed isolated unconjugated hyperbilirubinemia and a negative hemolysis workup. According to the lecture, what is the recommended next step for this otherwise healthy patient?

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Anti-mitochondrial antibody testing to exclude primary biliary cholangitis as a concurrent cause

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Liver biopsy to directly measure UGT1A1 enzyme activity in hepatic tissue

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Serum ALP electrophoresis to fractionate isoforms and confirm hepatic origin of any enzyme elevation

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No further evaluation is required; Gilbert's syndrome can be attributed in an otherwise healthy patient with isolated unconjugated hyperbilirubinemia once hemolysis is excluded

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Immediate initiation of phenobarbital to normalize bilirubin levels and confirm the diagnosis by therapeutic response

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In the clinical context of the article, the patient has confirmed isolated uncon...

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