Phenobarbital causes induction of smooth endoplasmic reticulum enzymes in the cells. As a result, the amount of active pharmaceutical ingredient decreases due to the following process:

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Activation of protein peroxidation

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Activation of microsomal oxidation

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Activation of uric acid synthesis

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Activation of lipid peroxidation

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Activation of glycolysis

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Phenobarbital causes induction of smooth endoplasmic reticulum enzymes in the ce...

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