In the early stages of lymphocyte development, the cell first needs to generate an antigen receptor. During this phase:

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Both chains of the receptor is generated simultaneously and then dimerise to form the mature receptor

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Each chain of the receptor is generated at different times

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The cell interacts with external antigens that direct the generation of antigen specific receptors

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The cell undergoes negative selection which determines if the cell is able to divide enough to generate lots of cells

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