Effect of cyanide
As you may know from reading detective fiction or watching crime shows, cyanide is a very rapidly acting poison. You suspect that it affects the respiratory chain and so you have designed an experiment to investigate its mechanism of action using techniques that you have just used to invesitgate DNP and MPP+. The results of your investigation are that upon addition of cyanide, oxygen consumption is inhibited when BOTH glutamate and succinate are used as substrates. From this, you conclude:

Question

Effect of cyanide  
 As you may know from reading detective fiction or watching crime shows, cyanide is a very rapidly acting poison.  You suspect that it affects the respiratory chain and so you have designed an experiment to investigate its mechanism of action using techniques that you have just used to invesitgate DNP and MPP+. The results of your investigation are that upon addition of cyanide, oxygen consumption is inhibited when BOTH glutamate and succinate are used as substrates. From this, you conclude:

Answer

Cyanide is acting as a respiratory chain inhibitor that interacts with Complex 1 since  it inhibits when both glutamate and succinate are used as substrates.

Answer

Cyanide is acting as an uncoupler since it inhibits the respiratory chain when both glutamate and succinate are used as substrates.

Answer

Cyanide is acting as a respiratory chain inhibitor that interacts with a component in Complex III  or Complex IV (or CoQ) since it inhibits when both glutamate and succinate are used as substrates.

Answer

Cyanide is interacting with the oxygen and preventing its uptake by the mitochondria.

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Effect of cyanide As you may know from reading detective fiction or watching ...

Effect of cyanide

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