The monoclonal antibody Rituximab (Anti-CD20) is a chimeric molecule, with both mouse and human components. Given the function of Rituximab, why do you think it was given a human heavy chain constant region?

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Answer

To bring Rituxmab into line with all other therapeutic monoclonal antibodies for dosage and treatment frequency.

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To prolong the half-life of the antibody in the patients, thereby improving its efficacy.

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To avoid an immune response in the recipients.

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To activate immune functions of the patient.

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The monoclonal antibody Rituximab (Anti-CD20) is a chimeric molecule, with both ...

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